Over the 9 years of surveillance, the fluconazole resistance rate continued to increase, rising from 5.7 (7/122) to 31.8% (236/741), while that for voriconazole was almost the same, rising from 5.7 (7/122) to 29.1% (216/741), with no significant statistical differences across the geographic regions. In addition, 16.9 (370/2192) and 71.7% (1572/2192) of the isolates were of non-wild-type phenotype to itraconazole and posaconazole, respectively. Overall, 22.2% (823/3702) of the isolates were resistant to fluconazole, with 90.4% (744/823) being cross-resistant to voriconazole. Antifungal susceptibility was determined by Clinical and Laboratory Standards Institute disk diffusion (CHIF-NET10-14, n = 1510) or Sensititre YeastOne (CHIF-NET15-18, n = 2192) methods. Species identification was carried out by mass spectrometry or rDNA sequencing. tropicalis isolates ( n = 3702) were collected from 87 hospitals across China. tropicalis causing invasive candidiasis in China, from a 9-year surveillance study.įrom August 2009 to July 2018, C. Here we report on the epidemiology and antifungal susceptibility of C. There have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. 12 Medical Laboratory Center, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, China.11 Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.10 Department of Laboratory Medicine, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.9 Department of Clinical Laboratory, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.8 Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, China.7 Department of Clinical Laboratory, Jiangsu Province Hospital, Nanjing, Jiangsu, China.6 New South Wales Health Pathology, Regional and Rural, Orange Hospital, Orange, NSW, Australia.5 School of Biomedical Sciences, Charles Sturt University, Orange, NSW, Australia. 4 Department of Infectious Diseases and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |